describe the structure of a DNA molecule as a double helix, including: • the importance of complementary base pairing between the 5’ to 3’ strand and the 3’ to 5’ strand (antiparallel strands) • differences in hydrogen bonding between C–G and A–T base pairs • linking of nucleotides by phosphodiester bonds
describe how the information in DNA is used during transcription and translation to construct polypeptides, including the roles of: • RNA polymerase • messenger RNA (mRNA) • codons • transfer RNA (tRNA) • anticodons • ribosomes