0610_s13_qp_32
A paper of Biology, 0610
Questions:
6
Year:
2013
Paper:
3
Variant:
2

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For Examiner's Use The kidneys remove metabolic waste from the liquid part of the blood. Name: the liquid part of the blood; the process that involves removing metabolic waste from the body. shows a kidney tubule and its associated blood vessels. X Y B Z A Describe the functions of the regions labelled A and B. A B For Examiner's Use Table 1.1 shows the concentrations of some substances in the blood at X, the fluid at Y and the urine at Z. Table 1.1 concentration / g per 100 cm3 substance blood at X fluid at Y urine at Z glucose 0.1 0.1 0.0 protein sodium ions 0.35 0.35 0.5 urea 0.03 0.03 2.0 Name the substance shown in Table 1.1 that: has molecules that are too large to pass through the walls of capillaries; is all reabsorbed in the kidney; is a metabolic waste product. Explain why the concentrations of sodium ions and urea are greater at Z than at Y. For Examiner's Use People who have acute kidney failure are given dialysis treatment. In dialysis machines, the blood flows through narrow tubes made from partially permeable membranes, surrounded by dialysis fluid. Dialysis fluid contains sodium ions. Use the information in Table 1.1 to suggest the concentration of sodium ions that should be in the fluid and give a reason for your answer. concentration g per 100 cm3 reason State two components of blood that are not in dialysis fluid. Heparin is added to the blood before it returns to the body from the dialysis machine. Heparin prevents a person’s blood from clotting. Describe the process of blood clotting.
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For Examiner's Use Antibiotics are used to treat human diseases. Many bacteria have become resistant to antibiotics. Some antibiotics can no longer be used to treat certain diseases. Samples of bacteria were taken from a person who had an infectious disease. They were spread onto four Petri dishes of agar (agar plates). Three of these agar plates contained the antibiotics 1, 2 or 3. The results are shown in . agar plate contains no antibiotic agar plate contains antibiotic 1 agar plate contains antibiotic 2 agar plate contains antibiotic 3 bacterial growth no bacteria key Explain why: no bacteria grew in the agar plate with antibiotic 2; bacteria grew in the agar plate with antibiotic 3; For Examiner's Use only a small number of bacteria grew with antibiotic 1. Explain why it is important to carry out a test similar to that shown in before giving an antibiotic to a person infected with a bacterial disease. Antibiotic resistance has become a major problem worldwide. Suggest how the problem of antibiotic resistance can be limited. For Examiner's Use Hormones are used to treat a variety of conditions. The most common hormonal treatment is the use of insulin to treat diabetes. Most of the insulin is produced using cells that are grown in large fermenters. These cells have been genetically engineered to produce human insulin. shows the stages involved in transferring the gene for insulin from human cells to bacterial cells. P gene from human cell removed from chromosome 11 Q bacterium produces human insulin R plasmid vector enters bacterium S gene for human insulin found to be on chromosome 11 T bacterium divides by binary fission V gene for human insulin inserted into a plasmid vector Put the stages into the correct sequence. Two have been done for you. S Q Diabetes is often treated with human insulin that has been produced by genetically modified cells. In most countries this type of insulin has replaced the insulin that was prepared from animals. Suggest the advantages of providing human insulin to people with diabetes rather than insulin obtained from animals.
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