9700_w09_qp_42
A paper of Biology, 9700
Questions:
10
Year:
2009
Paper:
4
Variant:
2

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Use Cell walls of bacteria contain peptidoglycans. Peptidoglycans are long chains of the sugars N-acetylmuranic acid (NAM) and N-acetylglucosamine (NAG) which alternate along the chain. A short peptide chain of three to five amino acids is attached to each NAM and these form cross-links with similar peptide chains from adjacent strands. shows a diagram representing part of a peptidoglycan structure. NAM peptide chains cross-link NAG NAM NAG NAM NAG NAM NAG NAM NAG NAM NAG Name the type of reaction that takes place to assemble the peptide chains that form the cross-links. Describe the mode of action of antibiotics, such as penicillin, on bacteria. Suggest the name of the type of enzyme that assembles the peptide chains that form the cross-links in peptidoglycans. Examiner’s Use State why antibiotics, such as penicillin, have no effect on viruses. Bacteria may be Gram-positive or Gram-negative. shows a diagram of part of the cell walls of both Gram-positive and Gram-negative bacteria. inner membrane peptidoglycan outer membrane inner membrane peptidoglycan periplasmic space Gram-positive Gram-negative Gram-positive bacteria cell walls have Gram-negative bacteria cell walls have a a peptidoglycan content of 50% peptidoglycan content of 10 – 20% Suggest why Gram-positive bacteria are more susceptible to the action of penicillin than Gram-negative bacteria. Examiner’s Use There is evidence that some bacteria have developed resistance to antibiotics. One form of pneumonia, a serious lung disease, is caused by the bacterium Streptococcus pneumoniae. The Canadian Health Service has carried out a survey to show how the resistance of S. pneumoniae to penicillin has changed over the last 20 years. shows the results of this survey. percentage of penicillin resistant S. pneumoniae year Describe the results shown in and explain how some strains of S. pneumoniae may have become resistant to penicillin.
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Use shows a section through part of a human testis. A B Name structures A and B. A ……………………………………………………… B ……………………………………………………… Spermatogenesis, the production of sperm, begins in the testes of a boy around the age of 11 and can continue for the rest of his life. outlines the sequence of events that occur during spermatogenesis. germinal epithelium spermatogonium cell division 1 stage C cell division 2 cell division 3 maturation cell D cell E cell F spermatozoan Examiner’s Use With reference to , state which cell division is mitotic, state which cells are haploid, state what is happening to the cell during stage C. The middle piece of a spermatozoan contains many mitochondria. Suggest why a spermatozoan needs so many mitochondria. Some couples have difficulty in conceiving. This could be due to a problem with either the male or female reproductive systems. Suggest reasons why a man may be infertile. Examiner’s Use In vitro fertilisation (IVF) is a widely used treatment for infertility. Explain what is meant by the term in vitro fertilisation. At one IVF clinic, over 1000 treatment cycles were monitored. The number of live births was recorded as a percentage of the number of treatment cycles for each age group. The results are shown in Table 5.1. Table 5.1 age of women/years percentage of live births per treatment cycle under 34 27.6 34 to 36 22.3 37 to 39 18.3 40 to 42 10.0 above 42 less than 5.0 The data in Table 5.1 show that there is a decrease in the percentage of live births per treatment cycle with increasing age. Explain this trend.
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Use Pompe disease is a rare neuromuscular disease caused by an autosomal recessive allele. This allele prevents the production of an enzyme called acid alpha-glucosidase (AG), which breaks down glycogen in muscle cells. Glycogen can build up in muscle cells causing damage to the cells. This damage leads to muscle weakness which gets worse with time. Explain how two parents, both of whom produce normal amounts of AG, can produce a child with Pompe disease. One form of treatment is enzyme replacement therapy where AG is given through regular injections. Suggest how AG may be manufactured. Name the hormone that stimulates the breakdown of glycogen in liver cells. State under what conditions glycogen would need to be broken down in liver or muscle cells. The MN blood group system is based on the presence of glycoproteins M and N, on the surface membrane of red blood cells, which act as antigens. State what is meant by the term antigen. Examiner’s Use The type of MN antigen on the surface membrane of red blood cells is controlled by a single gene with two alleles, LM and LN. The phenotypes of the MN blood group system are MM, MN and NN. Complete the genetic diagram to show how the MN blood group is inherited. parental phenotypes MN x MN parental genotypes gametes offspring genotypes offspring phenotypes Allele frequencies for LM and LN vary in different human populations throughout the world. Table 7.1 shows the LM and LN allele frequencies from five populations. Table 7.1 population allele frequency / % LM LN Canadian Inuit Egyptian German Chinese Nigerian Discuss the data shown in Table 7.1.
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Use In the majority of plants the leaf is the main photosynthetic organ. List four ways in which the structure of a dicotyledonous leaf is adapted for gas exchange. In an experiment to investigate the effect of light intensity on the rate of photosynthesis, the following procedure was carried out. ● Discs were cut, using a cork borer, from the photosynthetic tissue of the brown alga, Fucus serratus, a common seaweed of rocky shores. ● Ten discs were placed in each of four beakers containing 50 cm3 of sea water. The discs are denser than sea water and therefore initially sink to the bottom of the beaker. ● Each beaker was illuminated with a bench lamp placed at different distances, d, from the beaker. ● With time the discs began to rise to the surface of the water. ● The time, t, in minutes, at which the fifth disc from each batch reached the surface was recorded. ● The rate of photosynthesis was determined by calculating 1000 / t. A student’s set of results is shown in Table 8.1. Table 8.1 distance of beaker from lamp, d / cm light intensity 1 / d 2 time for fifth disc to reach the surface t / min rate of photosynthesis 1000 / t 0.04 43.5 0.01 27.8 0.004 19.2 11.4 Examiner’s Use Calculate the value for light intensity when the distance between beaker and lamp was 20 cm. Record the value in the space in Table 8.1. Explain why the discs rise to the surface after being illuminated for a length of time. Using the data in Table 8.1, describe the relationship between light intensity and the rate of photosynthesis. The student found that there was no increase in the rate of photosynthesis when two lamps were placed 5 cm from the beaker. Suggest why there was no increase in the rate of photosynthesis.