9700_s22_qp_13
A paper of Biology, 9700
Questions:
40
Year:
2022
Paper:
1
Variant:
3
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2
Four students were asked to match the function with the appearance of some cell structures in an animal cell. The functions were listed by number. mRNA passes through to the ribosome synthesis of polypeptides packaging of hydrolytic enzymes that will remain in the cell The appearances were listed by letter. V membranes which surround an enclosed inner cavity W non-membrane-bound, spherical structures X a double membrane interspersed with pores Y non-membrane-bound, cylindrical structures Z membrane-bound sacs, arranged as a flattened stack Which student correctly matched the numbered functions with the appearance of the cell structure?
1. Cell structure  →  1.2. Cells as the basic units of living organisms
6. Nucleic acids and protein synthesis  →  6.1. Structure of nucleic acids and replication of DNA
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14
Batrachotoxin is a poison found in frogs in the Colombian jungle. The poison is used to produce poison darts. The poison works by increasing the permeability of the cell surface membrane of nerve and muscle cells to sodium ions, which move out of the cells. Four students made statements about how the poison affects the cells. Water leaves the cells by osmosis, causing the cells to shrink. Water enters the cells by osmosis, causing the cells to burst. When the sodium ions move out of the cells the intracellular fluid has a more positive water potential than the extracellular fluid. When the sodium ions move out of the cells the extracellular fluid has a more positive water potential than the intracellular fluid. Which statements are correct for the cells affected by batrachotoxin?
4. Cell membranes and transport  →  4.2. Movement into and out of cells
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16
An indicator is colourless in acid and pink in alkali. In an experiment a petri dish of agar was prepared using an acidic solution of this indicator. A disc of agar 1 cm in diameter was removed from the centre to create a well. A white card showing circular marker lines 1 cm apart was placed underneath the petri dish. 1 cm3 alkali solution was put into the well in the agar and a stop-watch was started. A circular disc of pink colour appeared and spread through the agar. It reached the first marker line in a short time but took longer to reach the second marker line and a very long time to reach the third marker line. What explains these observations?
4. Cell membranes and transport  →  4.2. Movement into and out of cells
2. Biological molecules  →  2.1. Testing for biological molecules
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25
The sequence of bases in DNA coding for the first eight amino acids in the -polypeptide of adult haemoglobin is: CAC GTG GAC TGA GGA CTC CTC TTC However, in haemoglobin C, which is a cause of haemolytic anaemia, it becomes: CAC GTG GAC TGA GGA TTC CTC TTC Some of the DNA triplets that code for the amino acids are listed in the table. amino acid DNA triplet Glu CTC His GTG Leu GAG Lys TTC Pro GGA Thr TGA Which change occurs to the amino acid sequence of normal haemoglobin to make it haemoglobin C?
2. Biological molecules  →  2.3. Proteins
6. Nucleic acids and protein synthesis  →  6.2. Protein synthesis
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36
A student viewed three slides at both low magnification and high magnification. Each slide was a section through a different airway of the gas exchange system. The student observed three features in each slide. slide three features observed by student irregular arrangement of cartilage highly folded inner layer cilia on epithelial cells very few goblet cells cilia on epithelial cells thick layer of smooth muscle relative to wall thickness smooth muscle tissue blood vessels many goblet cells Which row correctly identifies the three slides?
9. Gas exchange  →  9.1. The gas exchange system
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38
Rheumatoid arthritis is a disease which causes the body’s immune system to attack its own cells. The disease can be treated using monoclonal antibodies. The table shows how five different monoclonal antibodies can work. monoclonal antibody mode of action binding to proteins on cell surfaces and triggering the immune system blocking molecules on cell surfaces that inhibit T-lymphocytes blocking cell signalling receptors that trigger cell division binding to antigens on cell surfaces and releasing a drug blocking cell signalling receptors that trigger the immune response Inflammation and swelling of joints are symptoms of rheumatoid arthritis. The cytokine, TNFalpha, activates cells in the immune system leading to death of cells in the joint. Which types of monoclonal antibody could be used to treat rheumatoid arthritis?
11. Immunity  →  11.2. Antibodies and vaccination
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39
A person’s blood group is determined by antigens present on the red blood cells. Antibodies in the plasma of the person who receives the blood can make some blood transfusions unsafe. The table shows the antigens and antibodies in the blood of people with different blood groups. blood group presence of A or B antigens on red blood cells presence of antibodies to A or B in plasma A A only anti-B only B B only anti-A only AB A and B neither O neither anti-A and anti-B Which blood groups can be given to a person with blood group A?
11. Immunity  →  11.2. Antibodies and vaccination
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40
Some of the events during the primary immune response are listed. phagocytosis of a foreign microbe by a macrophage and antigen presentation some T-lymphocytes will become T-killer cells which kill infected body cells the T-helper cell divides by mitosis to produce T-lymphocyte clones a T-helper cell with the complementary receptor binds to the antigens being presented What is the correct sequence of events during the primary immune response?
11. Immunity  →  11.1. The immune system
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